Here’s everything you need to know ahead of the clash…
Kick-off time
8pm UK time
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How to watch in the UK
Live on TNT Sports
Streaming on Discovery+
Injuries and suspensions
Basel: Kaio Eduardo (doubt)
Aston Villa: Tyrone Mings (out), Ross Barkley (out)
Predicted line-ups
Basel (4-2-3-1): Hitz; Tsunemoto; Barisic, Adjetey, Daniliuc, Schmid; Metinho, Bacanin; Shaqiri, Leroy, Otele; Broschinski
Aston Villa (4-2-3-1): Bizot; Cash, Lindelof, Torres, Maatsen; Onana, Bogarde; Sancho, Elliott, Malen; Watkins
Recent form
Basel are currently third in the Swiss Super League but have struggled in the Europa League. Having only won two of their opening five matches in the competition, they languish in 24th place, the final place that would go through to the round of 32.
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Villa are in excellent form having won seven of their last seven matches in all competitions. This run includes an impressive win over Premier League leaders Arsenal at Villa Park at the weekend.
What’s been said
Despite Villa’s good form, their manager Unai Emery believes that Basel will pose his side a tough test.
“The most important thing is how we are building the team, how we are achieving in our process during each competition.
“We need to try to show tomorrow how we can compete, how we can continue building our structure with the players in our tactical idea in Europe against Basel, because to play away is always difficult. To play in Europe is always difficult.
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“Basel are going to play at home and they won two matches at home in this competition. They are feeling strong through their stadium with their supporters and they will be facing us so, so motivated.”
Basel boss Ludovic Magnin is well aware of the challenge that his side faces against Villa.
“We know we’re facing a big challenge. I expect a tough game against a technically very strong opponent. We have to be prepared to suffer and also manage without possession for long stretches.
“But there are those magical nights at St. Jakob-Park. We want to bring the same energy to the stadium as we did against VfB Stuttgart, then anything is possible.”